Passionate about #GWAS #Metabolomics #Proteomics #Glycomics #Epigenomics, Professor @WeillCornell
Medicine - Qatar, Blog on http://metabolomix.com, http://suhre.fr
Karsten Suhre
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Urinary Single-Cell Transcriptomics in Kidney Transplantation: Elucidation of Donor–Recipient Cellular Dynamics and Fibrogenic Stress
www.sciencedirect.com/science/arti...
Interesting paper on the genetics of familial hypercholesterolaemia using WGS of 77,260 samples.
jmg.bmj.com/content/63/5...
I find the large number of variants in LDLR particularly interesting for further investigations into the structural factors of LDLR - APOB interactions.
Our paper is now available in the print edition of Proteomics:
"Comparative Analysis Between Olink-PEA and Alamar-NULISA Proteomic Technologies Applied to a Critically Ill COVID-19 Cohort"
dx.doi.org/10.1002/pmic...
Amazing what Claude AI is capable of, together we wrote this paper:
Genomic correlates of hyperthermostability revisited: a large-scale validation across 1,963 microbial genomes
2026 Claude AI written:
www.biorxiv.org/content/10.6...
2003 Suhre & Claverie, JBC paper:
www.jbc.org/article/S002...
Come and join me for a GenomeWeb webinar supported by Seer on
"Unbiased Plasma Proteomics Expands GWAS Insights"
Wednesday, March 11, 2026
12:00 PM Eastern Daylight Time
Register here:
event.on24.com/wcc/r/521498...
More details:
www.genomeweb.com/events
Using @somalogic.bsky.social affinity #proteomics data from three cohorts and #pQTL association strength as a readout we identify protein signatures reflecting latent variation in aptamer-based affinity proteomics.
Learn how HSP90 can act as a proxy for cell-lysis.
pubs.acs.org/doi/full/10....
Here a tutorial on how to easily 3D-print proteins and other macro-molecules:
makerworld.com/en/models/96...
Karsten Suhre
A study on 1.7 million people in Hong Kong shows superior hybrid immunity to Covid in people who got vaccinated before infection vs. people who got infected first. "Our findings are a direct rebuttal to arguments for natural immunity," the authors write. doi.org/10.1016/j.va...
Karsten Suhre
Quantifying the ∼75–95% of Peptides in DIA-MS Data Sets that Were Not Previously Quantified #JProteomeRes pubs.acs.org/doi/10.1021/...
Karsten Suhre
🧬 New preprint: "The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications"
Why do some genetically supported drug targets succeed in the clinic while others fail? Across 100,526 GWAS, the same evidence flags constrained gene functions rarely safe to modulate.
Karsten Suhre
Karsten Suhre
Karsten Suhre
Karsten Suhre
Carl Zimmer
BioMassSpec
David Ochoa
How to print 3D protein and molecular structures - from virtual to physicalThis is a 3D print of an antibody bound to a protein, i.e. PDGF-B blocking antibody bound to PDGF-BB. Blue and red are two su...
Accurate quantification of circulating proteins is critical for assessing biological variation and integrating proteomics with other omics to understand biological processes and disease mechanisms. Pr...
Genome-wide association analyses of blood plasma samples using a mass spectrometry-based platform illustrate the complementarity of different proteomics approaches for identifying protein quantitative...
We have developed a novel algorithm termed GoldenHaystack (GH) that was designed for enhanced peptide quantification of data-independent acquisition liquid-mass spectrometry (DIA-LC-MS) data files reg...
