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Studying the cell nucleus in search of inspiration for future DNA computers. Systems Biology professor at Karlsruhe Institute of Technology, post opinions mine alone. hilbertlab.org
Lennart Hilbert








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I will bombard you on bluesky with more material over the next days, no shame.
2d
Lennart Hilbert
1d
Special cameo of our favorite fish (c/o @lennarthilbert.bsky.social), for those interested! 🐟
πŸ”¬ The #EMBO | #EMBL Symposium "Mechanobiology across the tree of life" is well underway here in Heidelberg. πŸ’‘ Come by our booth to talk about #photomanipulation, laser ablation, #FLUCS, and custom microscopy solutions for #mechanobiology experiments. πŸ‘‹ See you at the booth! #EESMechanobiology
6h
Did you know that stem cells have unusually large transcription clusters, which disappear upon differentiation? Yes? You paid attention in 2018! In 2026, we show you that this process proceeds via massive, global shifts in transcriptional control. advanced.onlinelibrary.wiley.com/doi/10.1002/...
If you see this image and think "ha, fly testis!", you know your stuff. If you also know how transcription clusters form and disperse during sperm precursor formation, maybe don't read our new Advanced Science paper, out today πŸ˜‰ advanced.onlinelibrary.wiley.com/doi/10.1002/...
1d
In our new Advanced Science article, super-res imaging and cluster shape analysis show "Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface-Condensate Trajectory". Besides mESC, we also have zebrafish, fruit flies & simulations to show the process is conserved!
2d
We see in three model systems (including fruit fly testes) and in block copolymer simulations that "Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface-Condensate Trajectory". Here, we use a differentiation coordinate to trace cluster number, control state & shape.
Hear hear, Another fantastic collaborative project have seen the light! After a few years of backing...the manuscript on how "Stem cell differentiation disperses transcriptional clusters via a conserved surface-condensate trajectory" Is out πŸ₯³πŸ₯³ 🍾🍾πŸ₯‚πŸ₯‚ advanced.onlinelibrary.wiley.com/doi/10.1002/...
RAPP OptoElectronic
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W3 Professorship for Plant Biotechnology // University of Freiburg www.nature.com/naturecareer... The position holder will lead a research program that combines excellent basic research with clear perspectives for biotechnological and societally relevant applications. #BotanyJobs
Zebrafish Rock!
Lennart Hilbert
Lennart Hilbert
9d
advanced.onlinelibrary.wiley.com
Lennart Hilbert
Lennart Hilbert