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šŸš€ New preprint on bioRxiv! How do physical boundaries shape collective cell migration? We show that geometric confinement progressively suppresses ERK signaling waves and slows collective epithelial migration by pushing tissues into a mechanically compressed state. šŸ‘‰šŸ¼ doi.org/10.64898/202...
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Collective cell migration is a fundamental process in morphogenesis, tissue repair, cancer invasion, and frequently occurs under geometric confinement in vivo. However, how confinement interfaces with...
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Geometric confinement regulates ERK signaling dynamics and collective migration
Sylvain Gabriele