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So excited to see this out! Congratulations to @sarahehancock.bsky.social and everyone involved!
Dec 22, 2024
Ying Fei Liew
I'm so relieved to finally get this one up as a preprint. We started this project back in 2019 when we created our first gemcitabine (GEMC) resistant (GEMR) #PDAC cell line. We showed that GEMR upregulates lipid synthesis and that targeting different steps could sensitise cells to GEMC. 1/n ๐Ÿงช๐Ÿ‘ฉโ€๐Ÿ”ฌ
Dec 21, 2024
Sarah E Hancock
Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma https://www.biorxiv.org/content/10.1101/2024.12.18.628624v1