Scientific Editor, Cell. PhD (Cantab). Views my own.
Qian Cheng
I'm starting a new role as Scientific Editor at Cell @cp-cell.bsky.social. I look forward to reading the exciting advances emerging across computational biology and applied AI in biomedicine.
📨 Please feel free to get in touch with me to discuss your work at [email protected].
#Cell #AI4Science
A biophysically principled sequence model IceQream characterises complex Transcription Factor-DNA interactions from chromosome accessibility analysis.
@Akhiad.bsky.social
#BiotechNatureComms
www.nature.com/articles/s41...
Authors use Restricted Boltzmann machines trained on natural sequences to design new riboswitch aptamer domains and validate their functionality via chemical probing. @jorgefdcd.bsky.social
www.nature.com/articles/s41...
MINT, trained on large #PPI datasets, outperforms existing protein language models in predicting binding, mutations, and immune interactions.
@bergerlab.bsky.social #BiotechNatureComms
doi.org/10.1038/s414...
PyFuRNAce is an intuitive browser-based RNA design tool.
@monari-luca.bsky.social @kgoepfrich.bsky.social @uniheidelberg.bsky.social realized the largest cotranscriptionally folded RNA nanostructures to date. #BiotechNatureComms
www.nature.com/articles/s41...
𝘕𝘢𝘵𝘶𝘳𝘦 𝘊𝘰𝘮𝘮𝘶𝘯𝘪𝘤𝘢𝘵𝘪𝘰𝘯𝘴 @natcomms.nature.com has recently launched 𝗔𝗿𝘁𝗶𝗰𝗹𝗲𝘀 𝗶𝗻 𝗣𝗿𝗲𝘀𝘀. This provides early, citable access to accepted research, enables faster dissemination of findings, and supports a smoother publishing experience for authors.
𝗙𝗔𝗤 here: support.springernature.com/en/support/s...
A multi-scale, multi-context, and interpretable mapping strategy to map cells across space, time, and disease. @pcnmartin.bsky.social @wonkj.bsky.social
#spatialMapping #spatialOmics #BiotechNatureComms
www.nature.com/articles/s41...
MIRO is a graph neural network method that enhances spatial clustering for single-molecule localisation microscopy datasets. #BiotechNatureComms
@cmanzo.bsky.social @qubilab.bsky.social @giovannivolpe.bsky.social
doi.org/10.1038/s414...
Benchmarking scHi-C embedding methods shows that data representation, preprocessing options, and biological settings play a more important role in identifying cell states. @fulaijin.bsky.social
www.nature.com/articles/s41...
Using microfluidics and endogenous reporters, single cells are tracked to reveal how temporal dosing rewires chromatin in a model with near single-cell accuracy. @stevenwsmeal.bsky.social @robineclee.bsky.social #BiotechNatureComms
www.nature.com/articles/s41...
RNA nanotechnology creates structural and functional RNA architectures for biomedicine, synthetic biology and beyond. Here, the authors introduce pyFuRNAce, an intuitive browser-based RNA design tool....
Cis regulatory elements endow genomes with sequence-encoded logic to drive cellular differentiation. Here, the authors introduce a biophysically principled sequence model that characterises complex TF...
Protein language models capture single proteins but struggle with interactions. Here, authors present MINT, trained on large PPI datasets, which outperforms existing PLMs in predicting binding, mutati...
doi.org
What is an Article in Press? How is the Article in Press different to the VoR? Is the Article in Press citable? How does indexing work with an Article in Press? Can corrections/ amendments be m...
Riboswitches are allosteric RNA molecules that change conformation upon ligand binding to regulate downstream genes. Here, the authors use Restricted Boltzmann machines trained on natural sequences to...
Embedding is a key step in single-cell Hi-C analysis to identify cell states. Here, the authors benchmark 13 embedding methods in 10 scHi-C datasets. They find that data representation, preprocessing ...
The alignment of heterogeneous spatial samples has become a growing challenge. Here, authors present a multi-scale, multi-context, and interpretable mapping strategy to map cells across space, time, a...
Cells rely on limited numbers of transmembrane receptors to process signals from dynamic microenvironments. Using microfluidics and endogenous reporters, the authors track single cells to reveal how t...
