Scientific Computing Specialist @ AITHYRA
Opinions are my own
he/him
Stephan Köstlbacher
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New preprint! Cell division has to happen at the right place but how Archaea pick that place is unknown. We now identified a three-protein system, Dip, that positions the divisome at midcell in H. volcanii and is broadly conserved across Archaea. A thread 🧵
www.biorxiv.org/content/10.6...
Can vouch! I worked a lot with Dani and he's one of the most thoughtful, generous scientists I know. If you're into archaea and want a PI who invests in his people (and yes, the cake breaks are real), apply. You won't regret it.
Archaea the hornets of the microbial world. Discuss.
www.biorxiv.org/content/10.6...
TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria if you are a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.
Eukaryogenesis was about more than a proteobacterium hitching a lift with an archaeon. Genes from other kinds of bacteria came along for the ride, stitched together with viruses. Paper in @nature.com www.nature.com/articles/s41...
Excited to say that my new paper with @maxlechte.bsky.social (and others not on bluesky) has come out in @nature.com! Study of sediments, geochemistry and fossils from rocks 1.75 to 1.4 billion years old indicate that the oldest known #eukaryotes were aerobic and benthic!
#protists
rdcu.be/fjNgL
Chromatin organization in Asgard archaea: histones, SMC complexes, and the archaeal roots of eukaryotic chromatin: Trends in Genetics www.cell.com/trends/genet...
New review by @jvhooff.bsky.social & @damelab.bsky.social
We are excited to share a new preprint from Dimitris Dalkidis that identifies the effects of inhibitors DMPP and ATU in ammonia-oxidizing archaea! #archaea
"Common nitrification inhibitors exhibit varied physiological mechanisms on an ammonia-oxidizing microorganism"
www.biorxiv.org/content/10.6...
Do biofilms give an ecological advantage? Yes!
A fantastic follow-up to our previous biofilm work in ammonia-oxidizing archaea:
"Biofilm Lifestyle Drives Ecophysiological Niche Expansion in an Archaeal Soil Nitrifier"
www.biorxiv.org/content/10.6...
Congratulations to all authors! #archaea
Archaea kill bacteria, at least on occasion. The molecular underpinnings of these lethal interactions are barely understood. Here, we describe cinquedea, an α/β hydrolase secreted by the halophilic ar...
Phylogenomic reconstruction of the proteome of the last eukaryotic common ancestor sheds light on the origin of eukaryotes, indicating an important role of horizontal transfer of genes from diverse ba...
Nature - Integrated palaeontological, sedimentological and geochemical analyses of ancient rocks from Australia show that early eukaryotes were largely restricted to oxygenated benthic habitats,...
The genomes of organisms across the tree of life are structurally and functionally
organized into chromatin. In eukaryotes, within an organelle called the nucleus, chromatin
is shaped by histones and ...
www.cell.com
Archaea Biology Vienna
How do mitochondrial ribosomes keep pace with membrane insertion?
Now out in NSMB: We show that mitoribosomes slow down at defined positions linked to membrane insertion and protein topology: rdcu.be/fhqIT
#Mitochondria #Ribosome #CryoEM
I'm looking for an enthusiastic student to join my team as a PhD candidate on archaeal genome evolution 🦠💻
Work in beautiful Utrecht, at @binfutrecht.bsky.social, an international group full of caring, amazing scientists, and with frequent cake breaks!
www.uu.nl/en/organisat...
Please share! 🙏
Leigh Anne Riedman
🧵 New pre-print out from my time at @mib-wur.bsky.social
showing how the titration of the initiator protein DnaA on the chromosome of E. coli can generate stable DNA replication @hohlbeinlab.bsky.social @nicoc-micsynmet.bsky.social
doi.org/10.64898/202...
Nature Structural & Molecular Biology - Schöndorf and Petrychenko et al. show that mitochondrial translation speed is coupled to OXA1L-mediated inner membrane insertion, with...
