New preprint from the lab:
ATM controls fork processing and restart, and the PPM1D phosphatase is needed to properly balance this action of ATM.
Congratulations to @yitingcao.bsky.social @yingzhengwang.bsky.social and Jumana Badar.
www.biorxiv.org/content/10.1...
In response to DNA replication stress, DNA damage signaling kinases inhibit origin firing and promote the remodeling and stabilization of replication forks, leading to a systemic reduction in DNA synt...
