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by @jimpick.com
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I'm excited to share our recent working using forward genetics to identify virulence determinants in Rickettsia. Check it out! www.biorxiv.org/content/10.6...
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www.biorxiv.org
Lipopolysaccharide (LPS) is highly immunostimulatory, yet it is evolutionarily conserved among many obligate intracellular bacteria for unknown reasons. We report a forward genetic screen to identify ...
A genetic screen identifies O-antigen as essential for Rickettsia parkeri survival in macrophages by protecting from inflammasomes and interferon-stimulated genes
Thomas P200 Burke