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🆕 New paper out with Jean-Luc Imler and Rune Hartmann in EMBO journal. We dissect mechanisms of antiviral immunity and how STING is activated by FADD and DREDD during viral infection in Drosophila melanogaster. link.springer.com/article/10.1...
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STING is an evolutionarily conserved key regulator of innate immunity. In the model organism Drosophila melanogaster, STING activates the NF-κB-like transcription factor Relish, initially characterize...
link.springer.com
FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster - The EMBO Journal
Carine Meignin 🪰🦠🧬🌈