A back-to-back paper from Alanna Schepartz and @jhdcate.bsky.social groups shows how the E. coli ribosome supports the incorporation of the non-α-amino acid monomers! pubs.acs.org/doi/10.1021/...
Engineering the translation apparatus to accept backbone-modified amino acid analogues would enable the programmed synthesis of sequence-defined biopolymers with tunable properties. β-Hydroxy acids ar...
