Starting 2026 with Quan Pham's paper expanding the chemical toolbox for engineering AAV
- New bioorthogonal labeling, including IEDDA, for efficient macromolecule attachment
- Incorporation of two different chemistries for dual capsid labeling & much more:
onlinelibrary.wiley.com/doi/full/10....
We describe technology to introduce diverse non-natural chemical functionalities site-specifically into the capsid of adeno-associated virus through genetic code expansion, and using them to engineer...