#CrohnsDisease is associated with NOD2 mutations, but what's NOD2's role in the #intestine? Mckenna Eklund & @edanfoley.bsky.social show that #NOD2 interacts with #estrogen to regulate intestinal homeostasis, perhaps explaining the sex-specific pathogenesis of CD @plosbiology.org 🧪 plos.io/4ojTEuZ
