Scavenger receptor CD163 detoxes #hemoglobin (Hb) via haptoglobin–Hb (Hp-Hb) uptake, but can also bind free Hb directly. Richard Zhou & @parasitematt.bsky.social solve the CD163-Hb structure to reveal that CD163 arms allow receptor promiscuity when Hp is absent @plosbiology.org 🧪 plos.io/4eOLuIv