inMOTIFin is now published in Bioinformatics! 🎉
It lets you generate random sequences and TF motifs, and insert motif instances with custom spacing, co‑occurrence and orientation. Use cases for de novo motif discovery, cooperative TF binding, and DL explainability.
academic.oup.com/bioinformati...
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AbstractSummary. The accurate development, assessment, interpretation, and benchmarking of bioinformatics frameworks for analyzing transcriptional regulato
🚨 New preprint from group is now out on arXiv.
inMOTIFin: A lightweight, flexible simulation toolkit for regulatory genomics.
Simulate, implant, and modify transcription factor binding motifs with ease.
🔗 arxiv.org/abs/2506.20769
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Anthony Mathelier
The accurate development, assessment, interpretation, and benchmarking of bioinformatics frameworks for analyzing transcriptional regulatory grammars rely on controlled simulations to validate the und...
