Very excited to share our new paper out now in
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
Kim et al. uncover a role for U1 snRNP in regulating internal promoter activity. Beyond
its canonical role in splicing, U1 snRNP suppresses premature polyadenylation, enabling
upstream transcription t...