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Very excited to share our new paper out now in @MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...
May 16, 2025
Kim et al. uncover a role for U1 snRNP in regulating internal promoter activity. Beyond its canonical role in splicing, U1 snRNP suppresses premature polyadenylation, enabling upstream transcription t...
www.cell.com
U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation
Ana Fiszbein