A.d.i.d.a.s. All day I dream about science. Group Leader at IMBA. Genomics & evolution. Peruano.
Alejandro Burga
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New insights into #fertilization from the @pauligroup.bsky.social & Ikawa labs! In a tour-de-force study, we discovered ✨ SPARK ✨, a conserved sperm fertilization complex that couples sperm-egg binding to membrane fusion.
Read on 🧵👇 and check out our preprint for more details!
tinyurl.com/34cm4xat
How do sperm and egg fuse? Surprisingly, we still don’t fully know…
Our field has uncovered many pieces of the fertilization puzzle, but not how they fit together.
We identify ✨ SPARK ✨ - a conserved sperm complex that couples sperm-egg binding to fusion.
tinyurl.com/34cm4xat
Read on! 🧵👇
Video
tinyurl.com
How do sperm and egg fuse? Surprisingly, we still don’t fully know…
Our field has uncovered many pieces of the fertilization puzzle, but not how they fit together.
We identify ✨ SPARK ✨ - a conserved sperm complex that couples sperm-egg binding to fusion.
tinyurl.com/34cm4xat
Read on! 🧵👇
Pauli Group (posts by Andi Pauli)
Victoria Deneke
Video
Victoria Deneke
Our latest work is now online in NSMB: maternal yolk carries microRNAs from the intestine to embryos, shaping gene regulation and stress resilience in the next generation.
rdcu.be/fj8Er
#Epigenetics #microRNA #Inheritance @pasteur.fr @devstempasteur.bsky.social @erc.europa.eu
In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression an...