Almost missed that this is out! Former postdoc Liz Necka led this long overdue FMRI study formally comparing two types of pain modulation: Placebo analgesia & predictive cues. TLDR: these are NOT the same! Placebo analgesia reduced cue effects, & brain mechanisms were nearly all dissociable. 1/4
Lauren Atlas
New in #JNeurosci from Necka et al: External cues and treatments shape expectations about pain in different ways, and their mechanisms distinctly influence how people experience pain. https://doi.org/10.1523/JNEUROSCI.0050-25.2025