It’s well known that inflammation increases cancer risk, but how?
The answer: the epigenome "remembers" inflammation and primes stem cells for cancer.
Here is our paper: nature.com/articles/s41...
And a special shoutout to the lead author
@snaga13.bsky.social
A 🧵
Colonic stem cells retain a memory of inflammation following disease resolution and there is a mechanistic link between chronic inflammation and malignancy, suggesting potential strategies to mitigate...
