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The funder-researcher collaboration and open-access publisher for research in the life and biomedical sciences. Follow @eLifeCommunity.bsky.social
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Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability
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From brain databases and deep-learning methods to imaging and genetic modification techniques, eLife Tools and Resources articles present new techniques, datasets, software tools, and more. Take a look a the latest Tools and Resource articles: buff.ly/IpRQznE
Locus coeruleus modulation of prefrontal dynamics during attentional switching in mice
A context-free model of savings in motor learning
Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability
Drosophila ryanodine receptor gene triggers functional and developmental muscle properties and could be used to assess the impact of human <i>RYR1</i> mutations
Characterisation of cold-selective lamina I spinal projection neurons in the mouse
Our annual survey is your chance to have your say on the work we do. Have thoughts about our model for publishing? Share them here: buff.ly/IrRNIXl
This fundamental work demonstrates that ABHD6 regulates AMPAR gating kinetics in a TARP γ-2-dependent manner. The evidence in this study is compelling. This study will be of interest to readers in the field of synaptic transmission.
Dissociable neural substrates of integration and segregation in exogenous attention
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Intravital microscopy of meningeal macrophage Ca²⁺ dynamics reveals previously unknown population heterogeneity, vasomotion-coupled activity, and diverse responses during steady state and neuroinflammatory...
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Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability
Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding capacity...
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Locus coeruleus modulation of prefrontal dynamics during attentional switching in mice
α/β-Hydrolase domain-containing 6 (ABHD6) accelerates the desensitization and deactivation of TARP γ-2-containing AMPA receptors
Altmetric provides a collated score for online attention across various platforms and media.See more details
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Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability
Intravital microscopy of meningeal macrophage Ca²⁺ dynamics reveals previously unknown population heterogeneity, vasomotion-coupled activity, and diverse responses during steady state and neuroinflammatory...
buff.ly
A context-free model of savings in motor learning
Recurrent neural network models trained on a novel motor skill exhibit a persistent shift in preparatory activity that enables faster relearning, without cognitive or contextual cues.
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The Drosophila ryanodine receptor plays a conserved role in setting functional and structural muscle properties, regulates embryonic muscle development and could be used to assess the impact of human...
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Drosophila ryanodine receptor gene triggers functional and developmental muscle properties and could be used to assess the impact of human RYR1 mutations
Lamina I projection neurons that respond selectively to skin cooling receive monosynaptic input from Trpm8-expressing primary afferents and innervate brain regions involved in perception of cold and cold...
Characterisation of cold-selective lamina I spinal projection neurons in the mouse
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Dissociable neural signatures of integration and segregation provide the first direct neuroimaging evidence for the integration-segregation theory of exogenous attention.
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Dissociable neural substrates of integration and segregation in exogenous attention