Spatial Biology in the Kristensen lab at Aarhus University | Ph.D. using Deep Visual Proteomics in the Mann lab at University of Copenhagen
Frederik Post
My first PhD paper on the spatial characterization of colon organoids is finally out!
Thanks to @hausmannannika.bsky.social for spearheading this collaboration with me. Read more about the study in the post by @mannlab.bsky.social.
Frederik Post
Our paper is out in Nature today! We use Deep Visual Proteomics (DVP) to dissect α1-antitrypsin deficiency (AATD) in human liver at single-cell resolution.
Let us take a tour through proteotoxic stress in intact human tissue — one hepatocyte at a time.
www.nature.com/articles/s41...
Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood.
nature.com/articles/s41588-025-02089-2
#PediatricProteomics #pQTL
First author @liliniu.bsky.social explains ⬇️
This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.
High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing e...
www.nature.com
Out in @cp-cellsystems.bsky.social: Deep Visual Proteomics shows xenotransplantation drives colon #organoids toward in-vivo-like proteomes supporting their use in regenerative medicine; culture tweaks can mimic this shift. With @kimbakjensen.bsky.social. Lead author Frederik Post explains below:
Mann Lab
Mann Lab
Mann Lab
Very happy to share that part of my postdoc work @ucph.bsky.social @kimbakjensen.bsky.social lab is out now in @cp-cellsystems.bsky.social!
In close collaboration with @freddyomics.bsky.social @mannlab.bsky.social we show that orthotopically transplanted organoids recapitulate in vivo phenotypes 👇🏼
Out in @cp-cellsystems.bsky.social: Deep Visual Proteomics shows xenotransplantation drives colon #organoids toward in-vivo-like proteomes supporting their use in regenerative medicine; culture tweaks can mimic this shift. With @kimbakjensen.bsky.social. Lead author Frederik Post explains below:
