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Associate Professor. Cambridge Stem Cell Institute, University of Cambridge, UK. Interested in epithelial cell fate plasticity and early tumorigenesis.
Maria Alcolea
This is a lovely smiley face! 😊 Super excited to finally see our recent paper in print! 📖🎉 Check out how the precancerous fibrotic niche 🌱 determines nascent tumour persistence in the current issue of @nature.com🔬 www.nature.com/articles/s41... @gretas90.bsky.social, E.Rojo, @hariajith.bsky.social
1mo
Studying nascent tumour stages and microtumours 🔬 remains a significant challenge in our field 👩‍🔬 We’re thrilled to partner with FocalPlane to share the "behind-the-scenes" of studying what determines early tumour persistence www.nature.com/articles/s41... Greta Skrupskelyte, Eduardo Rojo
Excited to see our work featured at Cancer Cell @cp-cancercell.bsky.social ✨ This highlights nascent tumour persistence as a co-evolutionary process between tumour cells and their microenvironment 🌱 www.nature.com/articles/s41... www.cell.com/cancer-cell/...
Thanks for featuring our work on how emerging tumour remodel their nascent niche 🌱promoting their survival @cam.ac.uk, @scicambridge.bsky.social , @cruk-ci.bsky.social, @pdncambridge.bsky.social www.stemcells.cam.ac.uk/news/alcolea... www.nature.com/articles/s41...
2mo
1mo
Somatic genomics as a discovery engine for biomedicine - a Perspective in Cell www.sciencedirect.com/science/arti...
Maria Alcolea
3mo
3mo
Clonal competition eliminates most early neoplastic lesions, yet a subset persists and ultimately progresses. In Nature, Skrupskelyte et al. demonstrate that nascent tumors survive by actively reshapi...
www.cell.com
Precancerous niches as gatekeepers of tumor initiation
Maria Alcolea
Maria Alcolea
Somatic genomics as a discovery engine for biomedicine
Somatic mutations, or genetic changes occurring in cells after conception, are widespread in healthy tissues but are conventionally viewed as signs of…
www.sciencedirect.com
Maria Alcolea
Inigo Martincorena
Tracking nascent tumours in their earliest stages is one of the biggest hurdles in our field. In the latest blog post by Focal Plane (The Company for Biologists), we break down the specific challenges encountered in this journey. focalplane.biologists.com/2026/03/25/i...
2mo
Imaging spotlight: dissecting the precancerous niche - News
focalplane.biologists.com
Imaging spotlight: dissecting the precancerous niche - FocalPlane