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Finally online 🥳, the largest #QTL study ever done in mice, we use an actuarial approach to map #genetic factors affecting #aging in mice (Vita) and discover that genetics modulates the effect of #bodyweight on #lifespan (Soma). www.biorxiv.org/content/10.1...
Apr 30, 2025
www.biorxiv.org
The dynamics of lifespan are shaped by DNA variants that exert effects at different ages. We have mapped genetic loci that modulate age-specific mortality using a new actuarial method. We started with...
Genetic Modulation of Lifespan: Dynamic Effects, Sex Differences, and Body Weight Trade-offs
Danny Arends