Just published in Nature Reviews Chemistry - the Target 2035 roadmap for chemical probes for all! lnkd.in/gGqMUTVq
This excellent commentary is a must-read for cancer biologists (and all biologists, really).
Probing cancer with small-molecule tools—Progress and challenges: Cancer Cell www.cell.com/cancer-cell/...
Interested in Chromatin modifications & epigenetics in health, disease and development? Apply now to our GRC and GRS. Many speaker slots still to be chosen from abstracts!
www.grc.org/histone-and-...
...and kudo to Karina Machado and @dkoes.compstruct.org for their winning predictions and to @karlasatchell.bsky.social for the unwinding assays!
The latest research from the He Lab (www.hansenhelab.org) reinforces the importance of integrating epigenomic assays into clinical practice to enhance cancer patient care. Congratulations to the entire team!
@uhnresearch.bsky.social @pmresearch-uhn.bsky.social
doi.org/10.1038/s415...
Save $250 on registration for the joint Keystone Symposia meeting: The Ubiquitin Family in Biology and Disease / Proximity-Based Biology and Therapeutics. Register by Dec 29 (11:59 pm MST).
đź”— hubs.la/Q03Z5pcG0
@carrowsm.bsky.social @choudharylab.bsky.social
#KSUbiquitin26 #KSProximity26
⏰ Last chance! Submit your short talk abstracts for the joint #KSUbiquitin26 & #KSProximity26 meetings by Nov. 11 (11:59pm MT). Explore ubiquitin signaling & proximity-based therapies. 🔗 keysym.us/KSUbiquitin26, keysym.us/KSProximity26
@carrowsm.bsky.social @choudharylab.bsky.social
Do you know (or are you) a senior scientist in the USA who might like to move to Canada in the near future? The 2026 call for CERCs (Canada Excellence Research Chairs) was posted last month: 🧪 ⚛️ 🔠🇨🇦
Congratulations to our Senior Scientist Dr. Daniel De Carvalho for receiving the 2025 Peter Gilgan Canada Gairdner Momentum Award! 🎉
Read the media release here: www.gairdner.org/resource-hub...
Transcriptome-wide m6A RNA methylation profile in 162 primary prostate tumors identifies m6A association with prognostic clinical features and disease aggression.
The CERC Program offers eligible Canadian degree-granting universities the opportunity to establish research Chairs at their institutions in research areas that are of strategic importance to Canada.
On this day in 1879, Maud Menten was born in Port Lambton, Ontario.
In her work as a medical researcher, she became a leading expert in histochemistry and enzyme kinetics while fighting against sexism in her field.
Let's learn more about her life!
🧵1/10
2025 Canada Gairdner Awards recognize world-renowned scientists for transformative contributions to research impacting human health
The CACHE #2 preprint is now online: bit.ly/3DyCmHN Active learning and fragment growing delivered confirmed hits. A citizen scientist using the Fold-it gaming interface designed the top compound! Kudos to Sasha and Madhushika @thesgc.bsky.social at the bench. @conscience-network.bsky.social
Princess Margaret Cancer Centre
Our Cancer Cell Commentary reviews progress on chemical probes since Arrowsmith et al. (Nat Chem Biol 2015) and the launch of the Chemical Probes Portal. We highlight key issues, propose solutions, and outline a path to a quality probe for every human protein. #ChemicalProbes
Matthieu Schapira
Chemical Probes Portal
Congratulations to Dr. Daniel De Carvalho (@daniel-decarvalho.bsky.social) on winning the 2025 Gairdner Momentum Award! 🎉
His impactful work in cancer epigenetics is revolutionizing early detection and treatment. A well-deserved honour! đź‘Ź
đź”— www.uhnresearch.ca/news/gairdne...
NEW đź“°: We're delighted to see that our commentary on 'Probing Cancer with Small Molecule Tools' is featured in the journal @cp-cancercell.bsky.social raising awareness of the importance of choosing the right chemical probes and increasing the robustness of research.
sciencedirect.com
Chemical probes are powerful small-molecule tools in fundamental and translational cancer research. They are highly versatile, complementing genetic t…
