Great work on resistence mechanisms KRAS mutant CRC. Give it a read here:
Concurrent genetic and non-genetic resistance mechanisms to KRAS inhibition in colorectal cancer: Cancer Cell www.cell.com/cancer-cell/...
Combining exome sequencing and spatial transcriptomic profiling across patient-matched
CRC biopsies, Alonso et al. demonstrate that genetic and non-genetic resistance co-exist
in KRAS/EGFR inhibitor-r...
