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New preprint alert! Together with Tetsuya Yamamoto at Hokkaido University, we propose a “polymer micelle” model of transcriptional bursting. www.biorxiv.org/content/10.6...
www.nature.com/articles/s41... - from @igorulitsky.bsky.social - "most chromatin regions reported as bound by trans-acting RNAs in recent studies in mammalian cells appear to be technical artifacts"
Now it's @jpkreysing.bsky.social 's turn! 🎓🎉 Congratulations Jan Philipp on defending your PhD thesis, "Capturing Functional States in Situ with Cryo-Electron Tomography" in the @becklab.bsky.social lab! We're very excited to see more IMPRS-CBP #PhDs graduate🎓✨ #imprs_cbp #PhDlife #CryoET
What is the role of #poison-exon in regulating splicing factors in stem cells and development? Check out new work from Nathan Leclair and Mattia Brugiolo and many others in my lab @jax.org #RNA #splicing www.biorxiv.org/content/10.6...
@cpi-exstra.bsky.social @mixmue.bsky.social
'Scientific advancement depends on freedom, openness, and truth - the very values fascism eventually destroys. Our collective response will shape the future.'
📣 Preprint alert! We developed a method to analyze concurrent interactions between multiple chromatin regions at single alleles at sub-nucleosome resolution (multi-way Micro-Capture-C, mwMCC) & used this to study structural synergy within super-enhancers. 1/14 www.biorxiv.org/content/10.6...
We are offering Postdoc & PhD positions 🥼 If you are interested in the intersection of X chromosome inactivation, epigenetics, aging, sex-biased disease, and allele-specific multi-omics, feel free to reach out or share this with interested candidates. More info: portal.mytum.de/jobs/wissens...
How do we assess research excellence in a way that reflects today’s scientific reality? 🧪 Read the report from EMBO’s recent #policy workshop exploring this question: https://www.embo.org/wp-content/uploads/2026/04/Revisiting-the-EMBO-Funding-Criteria-A-Workshop-Report.pdf DORA CoARA
🚨 1/5 Check out the 2nd preprint from our lab on how IRES-mediated translation of synthetic circRNAs is employed in cells and in cell-free translation extracts, a highly collaborative effort with @immagina.bsky.social & the labs of @andershlund.bsky.social and CK Chen www.biorxiv.org/content/10.6...
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Many long noncoding RNA–DNA binding peaks detected using common assays arise from technical artifacts.
www.nature.com
Widespread DNA off-targeting confounds RNA chromatin occupancy studies - Nature Biotechnology