🚨Job alert in theory/math devbio 🚨
I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the amazing things embryos can do. We are based in a beautiful part of Scotland! Please share! www.abdn.ac.uk/jobs/vacanci...
Congratulations to Vikas Trivedi & collaborators for being awarded the HFSP grant!
An international team coordinated by EMBL Barcelona researchers has been awarded $1.5M to study how developing organisms stay on track despite climate-driven temperature instability.
www.embl.org/news/awards-...
How does a relatively simple tube become a complex brain? 🧠
One of the most dramatic transformations in development!
We built a framework to map exactly what changes. 🧵
New preprint from my postdoc at @nerurkar.bsky.social lab:
doi.org/10.64898/202...
Our latest: Minimal essential requirements for neural tube self-organisation
How does a single cell give rise to a tissue with the right cell types in the right proportions?
We deconstruct and rebuild a self-organising tissue from first principles
A thread🧵
www.biorxiv.org/content/10.6...
Glad to see this out in its final form!
www.nature.com/articles/s41...
What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers 🙏
A real computational tour de force by @ericneiva.bsky.social, carried out as Marie Skłodowska-Curie postdoctoral fellow in the team, now published in the Journal of Computational Physics: urlr.me/AuzK86
Congratulations, Eric!
@cnrsbiologie.bsky.social
Grateful to @ec.europa.eu for funding support
EMBL
Nimesh Chahare
The reliable generation of diverse cell types in precise proportions is essential for the formation of functional tissues during embryonic development. Three-dimensional organoid models derived from p...
We are hiring!
Come work with us in sunny Barcelona. We are looking for a Postdoctoral Researcher to study neuronal degeneration in Alzheimer’s Disease. Please help spread the word, and feel free to contact me if you have any questions.
ibecbarcelona.eu/postdoctoral...
Just published in @science.org 🚀
By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes.
A new platform for tissue engineering and the design of smart active materials!
www.science.org/doi/10.1126/...
An international team coordinated by Vikas Trivedi at EMBL Barcelona has been awarded an HFSP grant worth $1.5 million (€1.3 M) to study how developing organisms stay on track despite climate-driven t...
www.embl.org
Now published. Congrats to Soham and all co-authors! www.science.org/doi/10.1126/....
@embl.org
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...
Here our latest work on how morphogens trigger tissue phase transitions to tune their own length-scales and time-scales - An exciting collaboration with @zhvas.bsky.social @dianakhorom.bsky.social Bernat Corominas-Murtra and heroic experiments by the incredible @cami-autorino.bsky.social @embl.org
Just published 📢
@herveturlier.bsky.social and I show how the most advanced unfitted finite elements can increase our capacity to investigate fundamental problems in cell morphogenesis.
👉 Link to paper: doi.org/10.1016/j.jc...
🚀 Stay tuned for future applications to animal systems!
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.
The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter #TissueEngineering
We thought we were just studying mesoglea biogenesis…Turns out Nematostella has been hiding a sophisticated backup pressure valve! Work driven by the talented PhD student Soham Basu! @embl.org www.biorxiv.org/content/10.1...
Nicoletta Petridou
Video
Video
Pau Guillamat
🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨
“A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶
🔗 www.biorxiv.org/content/10.1...
#devbio #biophysics
🧵⤵️
Aissam Ikmi
Eric Neiva
Video
Very excited to share a new preprint by @ericneiva.bsky.social who developed a first-of-its-kind finite element method for simulating 3D cellular dynamics with coupled surface–bulk flows and signaling. A technical tour de force with broad applications in mechanobiology & beyond tinyurl.com/bdfhfke3
