🧬CGEN is hiring postdocs!🧬
We are looking for talented postdoctoral researchers to join our center: www.nature.com/naturecareer...
Exciting Expansion at CGEN! We’re thrilled to welcome Fena Ochs and Niels Erik Møllegaard. 🔬 Fena brings cutting-edge expertise in 3D chromatin organization and its role in gene regulation, DNA repair, and cell division. 🧬Niels Erik’s expertise is in genome structure and DNA helix conformation
Excited to share the latest paper from CGEN just published in Molecular Cell! This study demonstrates the specificity of RNAPII-CTD kinases CDK9 and CDK12, and also describes the activation mechanism of CDK12/13 in cells by the PAF1C subunit CDC73.
authors.elsevier.com/sd/article/S...
We’re excited to share that our postdocs, Catarina Pechincha and Sofia Ramalho from the Bekker-Jensen group, have been awarded prestigious EMBO Postdoctoral Fellowships! Big congrats to both! 👏
New review in Genes and Development: genesdev.cshlp.org/content/earl... Blear & Svejstrup review a critical transcription QC checkpoint at the beginning of protein-coding genes, where the cell assesses RNA polymerase II quality and decides whether it will continue, or not. @jsvejstrup.bsky.social
🌟 Check out the latest preprint from our center 🌟
This work brings us one step closer to gaining a deeper understanding of gene expression regulation - a core mission of our center 🧬 🧫
If you want to know more about CGEN visit our website: cgen.ku.dk
@dg.dk @ucph.bsky.social
Four of our six Master's students successfully defended their theses last week. In the coming weeks, the remaining two will defend theirs, and Mads, our laboratory technician trainee, will also complete his training. Last Friday, we held a joint celebration at the center. Congratulations to all! ⭐
Extremely proud to share the impressive work done by Anouk Olthof et al. on how cells maintain healthy levels of RNAPII, and how they respond when levels are too low. Fascinating stuff, we think www.biorxiv.org/content/10.1...
Interested in measuring RNAPII elongation rates? We developed DRB/TTchem-seq2 to directly measure rates across 3,000+ genes 🧬
genome.cshlp.org/content/earl...
This fantastic work led by Haiyue Liu reveals gene and intra-genic variation, links to histone marks & elongation factors
Details below! 👇
Center for Gene Expression (CGEN)
Center for Gene Expression (CGEN)
Center for Gene Expression (CGEN)
Center for Gene Expression (CGEN)
I’m very happy to share Zhong Han’s beautiful work on the biochemical function of Senataxin, encoded by a gene that is mutated in rare and early-disabling neurodegenerative diseases. Turns out it rescues backtracked RNA polymerase II during early transcription! www.sciencedirect.com/science/arti...
