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The brain microenvironment modulates FGFR1 activity in a host age-dependent manner to promote estrogen receptor-positive #breastcancer #brainmetastases @cittellylab.bsky.social @morgan-fox.bsky.social @cucancerbio.bsky.social @cucancercenter.bsky.social doi.org/10.1038/s414...
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FGFR1 amplifications are associated with risk of late recurrence for estrogen receptor-positive breast cancer. Here, the authors show that the brain microenvironment modulates FGFR1 activity in a host...
Brain FGF2 and NCAM1 contribute to FGFR1-dependent progression of estrogen receptor-positive breast cancer brain metastases - Nature Communications
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Nature Communications