New pipeline to identify drugs blocking #malaria transmission
It combines a high-throughput in vitro assay & a mouse model, enabling evaluation of compounds targeting the parasite's mosquito-infecting forms
@SwissTPH.ch
The Biomolecular Screening Facility has contributed to a successful collaborative study led by Till Voss (Swiss Tropical and Public Health Institute, University of Basel), resulting in the development of a robust, all in one pipeline for the discovery and testing of transmission blocking drugs against Plasmodium falciparum. This multidisciplinary effort combines a high-throughput in vitro assay with a novel in vivo model, enabling systematic evaluation of compounds that target mature stage V gametocytes - the only forms of the parasite that infect mosquitoes.
