Mapping of DNA-binding sites for 139 E. coli transcription factors
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A neural network that predicts binding energy from DNA sequence and can be used to design new binding sites
#NeuralNetworks #MachineLearning #Genomics
The authors describe BoltzNet, a neural network that learns the energy of transcription factor (TF)-DNA binding from genomic data and can be used to design new binding sites. They report the in vivo mapping and BoltzNet modeling of 139 E. coli TFs.
