Out today at @cellpress.bsky.social from @zernickagoetz.bsky.social and @slavov-n.bsky.social
www.cell.com/cell/fulltex...
I watched Lisa Iwamoto-Stohl lead this project over several years with incredible resilience. Some of the most technically challenging experiments I've ever seen!
Single-cell proteomics finds asymmetries between sister blastomeres from the 2-cell
stage in human and mouse embryos, defining two states: alpha and beta. Alpha-beta
asymmetry can be traced back to th...