Postdoctoral researcher at @radaiglesiaslab.bsky.social | Developmental genomics | preLighter (The Company of Biologists) | Artistic & Creative | Passionate about visual storytelling and design
María Mariner
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🚨Happy to share a new PreLight covering the latest #preprint by the Meissner lab (@molgen.mpg.de) on acute SUZ12 degradation during TLS formation. A work brilliantly executed by @dannimklee.bsky.social et al. Get to know more about him and his work here ⤵️ prelights.biologists.com/highlights/t...
Pairing acute SUZ12 degradation + simplified embryoids, Ming-Kang Lee et al. pinpoint time-dependent sensitivities to PRC2 loss. A meticulous experimental approach applicable to the functional stage-s...
This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...
This graph basically shows that the MSCA are, as of now, useless unless the EU governance does something about it 🧪
Our latest: Minimal essential requirements for neural tube self-organisation
How does a single cell give rise to a tissue with the right cell types in the right proportions?
We deconstruct and rebuild a self-organising tissue from first principles
A thread🧵
www.biorxiv.org/content/10.6...
Ahead of International Women’s Day on March 8, we’re sharing the female scientific role models who inspire our colleagues—one per day. Today Postdoc Irene Talon from the Vallier Lab. #InternationalWomensDay #IWD2026 #WomenInScience
Craig Kaplan
Out now in Science! Our study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵
www.science.org/doi/10.1126/...
The reliable generation of diverse cell types in precise proportions is essential for the formation of functional tissues during embryonic development. Three-dimensional organoid models derived from p...
In full agreement with this Career Feature article by @keepitonthehdl.bsky.social for @nature.com:
www.nature.com/articles/d41...
Turia came into our lives right on time, and she brought light, fun, and so many wonderful hikes! 🐕🏔️💙@sanchezgaya.bsky.social
There are so many fun ways to approach research dissemination!
Tried the @prelights.bsky.social spotLight video format to share our latest published work on how ZIC2 shapes early neural development!
Total YouTuber vibes: and I kinda' loved it, tbh. 🤳🔬👇
youtu.be/V_yMoWMkZCM
Orgullo de empollona, por Delia Rodríguez
elpais.com/opinion/2026...
@elpais.com
MadScientist
James Briscoe
Max Planck Institute for Molecular Genetics
el apoyo a las familias afectadas y el impulso a la investigación científica que permita mejorar el diagnóstico, el tratamiento y la calidad de vida de quienes conviven con estas patologías. #diamundialenfermedadesraras #rarediseasesday
How intrinsically disordered regions (IDRs) shape chromatin binding and nuclear organization of transcription factors (TFs) remains unclear. We used proximity-assisted photoactivation (PAPA), a single...
Transcriptional adaptation (TA) is a genetic robustness mechanism through which mutant messenger RNA (mRNA) decay induces sequence-dependent up-regulation of so-called adapting genes. How cytoplasmica...
the cutoff scores for #MSCA postdoc fellowships are very high this year. has the score distribution shifted compared to previous years? I made a plot with scores from past years.
if scores are at ceiling level, the process becomes essentially a lottery, because minor issues can lead to deductions.