BREAKING:
New proposed OMB regulation, applying to all federal grants, requiring grant reviews by senior political appointees and re-emphasizes that "peer review remains advisory and does not replace agency discretion".
#standupforscience
public-inspection.federalregister.gov/2026-10817.pdf
Happy to have the chance to share this commentary by @will-milligan.bsky.social & me:
rdcu.be/fldBs.
This is North Korea level bullshit, and a total fucking disaster for science and for the United States alike.
It doesn't matter whether it fails to pass; this kind of thinking is already penetrating NIH, NSF, NASA, etc and causing severe harm.
NASEM, AAAS, AAUP, etc must condemn unequivocally.
I'm excited to share that our work studying gene dosage response curves (GDRCs) is now out in Cell Genomics (@cellpress.bsky.social).
www.cell.com/cell-genomic...
[1/n]
Some deep work by my former student Matthew Aguirre on what the properties of cis- and trans eQTLs can teach us about the structure of gene regulatory networks!
Now published: journals.plos.org/plosbiology/...
"An email from NIH’s National Institute of General Medical Sciences (NIGMS) to research-center grantees, seen by Science, requires their institutions to promise that U.S. authors of papers NIH has flagged because of foreign co-authors will not collaborate with them in the future."
public-inspection.federalregister.gov
“Eddy received a letter from the [NIH], informing him that his work "had been determined to be of absolutely no value to the US taxpayer, and therefore it was being specifically terminated," he recalls. Eddy says he has given up on any dream that his funding would be restored”
Nature Reviews Genetics - In this Comment, the authors argue that understanding the genetic basis of adaptation requires considering the genetic architecture and ecological properties of traits...
Critics say bill would weaken U.S. science by cutting flows of ideas and talent
www.science.org
Milind et al. explore why loss-of-function variants and duplications tend to have
average effects in the same direction on 94 complex traits. Using gene dosage response
curves (GDRCs), they gather evi...
postdoc alert 🚨! NIH-funded postdoc in my lab to work on Ancestral Recombination Graphs in space. Please spread the word widely in your networks, and please reach out if you're interested! (2-3yr position, start date flexible, pay/benefits good!).
details here: careers.umich.edu/job_detail/2...
Shut Delaney Hall down, NOW.
Today, @menendez.house.gov and I went to Delaney Hall because of the inhumane conditions we've been hearing about.
What I saw and heard is absolutely unacceptable.
Carl T. Bergstrom
Nikhil Milind
Video
Jonathan Pritchard
Multiple positions available: Postdoc PhD students
Mutation rates per generation are strikingly similar across germlines of animals and across at least one somatic cell type, suggesting a key role for natural selection in shaping mutation rates. This ...
“Units of the NIH are privately directing grantees to request permission in advance for any co-authorship with a scholar affiliated with a foreign institution, even if all the work was done in the United States.”
Grantees also told to remove papers with foreign authors from progress reports.
Happy to share that this is now out in Cell Genomics and a featured paper for Multi-Journal Submission from @cellpress.bsky.social — many thanks to the editorial team + our reviewers!
Short recap + some further thoughts on the paper ⬇️ [1/7]
www.cell.com/cell-genomic...
Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social,
@natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n
I keep thinking I’m done being shocked. It is abundantly clear there is a vendetta against anything that gives joy or laughter and helps people.
I cannot believe the brilliant researchers who have been targeted and criminalized. Easy to demolish, hard to rebuild.
www.npr.org/2026/05/21/n...
NIH, NASA grantees are confused and concerned amid agencies’ piecemeal communication
Germline mutation rates per generation are strikingly similar across animals, despite vast differences in life histories. Analogously, in at least one somatic cell type, mutation rates at the end of l...
Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear.
Thrilled to share the second half of my PhD work here!
We show how data on expression quantitative trait loci (eQTL) relates to the structure of gene regulatory networks (GRN). Much of the GRN / eQTL picture is unmapped, but what we do have says a lot… (1/)
doi.org/10.1101/2025...
