Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.
Scripps Research
Researchers at Calibr-Skaggs are developing CLF065, a regenerative GLP-2 therapy, into two Phase 2 IBD studies. The studies aim to bring a regenerative treatment option to patients living with IBD, who currently have few therapies that repair the damaged intestinal lining.
At Scripps Research and Calibr-Skaggs, scientists are developing regenerative medicine therapies designed to help the body repair itself from within. Researchers are exploring new approaches for heart failure, IPF, IBD, age-related macular degeneration and more.
We got to see drug discovery up close inside Associate Professor Michael Erb's laboratory, where his team combines chemistry and biology to develop proximity-inducing drugs using automated machines to help synthesize and test thousands of compounds at once.
Congratulations to Asst. Prof. Alejandra Mendoza, recipient of a Health Innovator Award from the Kenneth Rainin Foundation! The grant will support her project, “Neuro-immune Networks in Chronic Intestinal Inflammation,” focused on advancing IBD research.
The Baran lab reports a new stereoretentive radical-radical cross-coupling reaction that enables alkyl–alkyl bond formation while maintaining 80–96% enantiospecificity. Published in Science Magazine, the method works across a range of pharmaceutically relevant molecules. https://ow.ly/lvyP50Za5tw
An experimental HIV vaccine regimen from scientists at Scripps Research and Karolinska Institutet elicited apex-targeted cross-neutralizing antibodies in every preclinical model tested. Published in Nature the vaccines generated responses against multiple HIV strains. More: https://ow.ly/pfKk50Z5Hcp
At some point in the aging process, the body loses its ability to regenerate cells, organs and tissues. Scripps Research President and CEO Peter Schultz and Associate Professor Michael Bollong want to understand when that is. More: https://ow.ly/mkXX50Z7IwS
Congrats to Daniel B. McClatchy, recipient of the Al Yergey Mass Spectrometry Scientist Award from the ASMS. McClatchy was recognized for pioneering advances in neuroproteomics, including SILAM and PALM workflows for quantitative in vivo proteomics. More: https://ow.ly/I0Bj50Z6lrx
Meet Kristal Stevens, a 3rd-year PhD candidate in the Bollong lab studying regenerative therapies through the Hippo pathway. Outside the lab, she channels the wonder of science into vibrant artwork—one of which was featured on the cover of ChemBioChem in February 2025.
Congrats to Dylan Pilz, a research programmer in Kristian G. Andersen's lab, who received the best poster presentation award at the Wastewater & Environmental Surveillance Meeting 2026 in Ghana! A @pha4ge.bsky.social member, Pilz was recognized for his work on wastewater genomic surveillance.
Scripps Research
Scripps Research
PHA4GE member Dylan Pilz won best poster presentation at the Wastewater & Environmental Surveillance Meeting 2026 in Ghana for work on rapid detection of cryptic SARS-CoV-2 variants in South African wastewater.
