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Neuroscientist and Research Director @CNRS. «Orientation&Coordination» team. Head direction, interneurons, memory. Saints-Pères, Paris 👩‍🔬🧠
Desdemona Fricker









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'The postsubiculum as a head-direction cortex' by Adrian Duszkiewicz, Desdemona Fricker, Andrea Burgalossi & Adrien Peyrache @adrian-du.bsky.social @desdemonafricker.bsky.social @apeyrache.bsky.social www.cell.com/trends/neuro...
🧠 Looking forward to Mark Brandon’s visit ! His work on Head Direction coding changed how we think of the neural compass: Network gain maintains a memory trace of previous experience. 🗓️ Join us for his seminar on April 3rd at 11h30 📍45 rue des Saints-Pères, Paris
Hi BlueSky — I’m bringing over an old SciTwitter thread series exploring how beautifully the vestibular system works from a systems and computational neuroscience perspective. Chapter 1 coming shortly! I’ll keep all chapters threaded below.
3mo
2mo
3mo
New paper alert! 🚨 We found that the brain's compass is remarkably stable at two scales 1️⃣ the system maintains its internal organization for weeks 2️⃣ It "remembers" its orientation for weeks, even after a single visit This may be key to how the brain aligns its other maps. Paper: rdcu.be/e3waP
We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:
Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr
La @semaineducerveau.bsky.social arrive bientôt au SPPIN ! Nous avons le plaisir d’accueillir une conférence suivie d’une visite du laboratoire par @uligraupner.bsky.social dédié aux approches optogénétiques pour comprendre les circuits neuronaux et le comportement.
4mo
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2mo
Active locomotion predictively rescues head direction attractor dynamics in head-fixed mice https://www.biorxiv.org/content/10.64898/2026.01.12.698940v1
4mo
Trends in Neurosciences
Desdemona Fricker
Thrilled to see our paper published! I’m deeply grateful to the amazing @ggirardeau.bsky.social for trusting me to develop and carry it out. Many thanks as well to @azulsilva.bsky.social , @belalima-paiva.bsky.social and Eleonore for driving this work forward together. www.nature.com/articles/s41...
5mo
If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd parisneuro.ovh
Jean Laurens