New preprint from the lab by Dennis Feigenbutz et al.: Using #snRNA-seq, we explore vulnerability profiles of cortical cell types in #HuntingtonsDisease mice and identify ER-phagy as a new pathway in HD pathogenesis.
www.biorxiv.org/content/10.1...
www.biorxiv.org
A common feature of neurodegeneration is selective vulnerability, where certain neurons succumb to disease, while others remain spared. The molecular underpinnings of these differences remain elusive....
