Reactome is an open source curated pathway database that provides pathway and network analysis tools for life science researchers.
Reactome
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Release News: V96 of #Reactome is live! 🎉
We have new and updated topics and pathways in Developmental biology, Disease, Immune system, Metabolism, Muscle Contraction, and more.
💡 Read more about V96 here :https://reactome.org/about/news/291-v96-released
👏 Thank you to our contributors, authors who have provided expert content and guidance, and peer-reviewers who provide feedback and ensure that everything entering Reactome is accurate. If you are interested in contributing, please reach out to us at [email protected]
🧠 We love to learn about how #Reactome empowers your research. If you have one to share, please reach out to us ([email protected]) to submit your work for our monthly spotlight!
Tsai et al. propose a framework to evaluate transcriptomic data through two paradigms: Key Characteristics (KCs) of chemical compounds - expert-defined properties of chemicals associated with specific human health hazards - and pathway annotation databases.
Check out our Reactome Research spotlight!
A 2026 Nature Genetics study found 13 genetic loci linked to susceptibility to SARS-CoV-2 Omicron infection. Reactome analysis showed these genes are enriched in glycosylation pathways, pointing to host glycan biology as a key factor in viral infectivity
Overall, the results suggest the proposed workflow may be a useful tool for systematic integration of transcriptomics into chemical hazard assessment.
🔗Read more at: reactome.org/content/reac...
Check out our selection for our latest #ReactomeResearchSpotlight! 💡
In their March 2026 Society of Toxicology paper, “A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets”.
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Reactome
Reactome
Reactome
Reactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge.
