Check our new preprint by Knopp M. et al.!
Human gut microbiomes can impose strong +/- selection for resistant versions of resident opportunistic pathogens. In the case we follow up, selection is driven by altered carbohydrate utilisation that the resistant mutant evolves. doi.org/10.64898/202...
doi.org
Typas Lab
Missed this paper last week, very interesting by Ami Bhatt and her group.
www.nature.com/articles/s41...
'Transposable elements are driving rapid adaptation of Enterococcus faecium'
Less than 1 week to apply for this postdoc!
If you want to find out more about the project have a look at our recent preprint: www.biorxiv.org/content/10.6...
#mevosky
www.biorxiv.org
Really happy to see this out! Great work led by @mboum.bsky.social
A nice example of how microbiome-specific ecological constraints can shape E. coli growth www.pnas.org/doi/10.1073/... @pnas.org
Why does antibiotic resistance evolution vary between patients?
Come to @officialuom.bsky.social @mermanchester.bsky.social to help us find out!
2.5 year @wellcometrust.bsky.social postdoc position in experimental evolution
Closing 15 May. Apply here: www.jobs.manchester.ac.uk/Job/JobDetai...
A new method for inference and tracking the transmission of strains in metagenomes #MicroSky #MicroEco www.nature.com/articles/s41...
Willem van Schaik
Michael Brockhurst
Why does antibiotic resistance evolution vary between patients?
Come to @officialuom.bsky.social @mermanchester.bsky.social to help us find out!
2.5 year @wellcometrust.bsky.social postdoc position in experimental evolution
Closing 15 May. Apply here: www.jobs.manchester.ac.uk/Job/JobDetai...
The TRACS algorithm tracks bacteria, viruses and parasites in metagenomic or population sequencing data, detecting microbial transmission even when multiple strains coexist within a host.
Over three decades, rapid expansion of the transposable element ISL3 has reshaped Enterococcus faecium, which helps to explain this pathogen’s growing clinical threat.
New paper out in @pnas.org 🎆!
Across healthy humans, the same bacterium encounters markedly different gut microbiomes.
How does this shape the ecological interactions it experiences?
We explored this focusing on commensal E. coli.
www.pnas.org/doi/10.1073/...
Image: @illuzation.bsky.social