New paper out! Looking at RNA-related pathways in neuronal remodeling, we found UAP56, an mRNA export factor. Actin disassembly is a likely target, both in dendrites and at presynapses. Also: cofilin is required for presynapse pruning. Please check out - journals.biologists.com/jcs/article/...
Neurite and synapse pruning are conserved mechanisms that adapt neuronal circuitry to different developmental stages. Drosophila sensory c4da neurons prune their larval dendrites and their presynaptic...
