Nice to see this story out! The idea that viral mimicry is an intrinsic feedback mechanism for sensing cellular dysregulation is fascinating and this paper explores this idea really well.
It was inspiring to be part of this collaborative work. Thanks to @bengrbm.bsky.social and the rest!
An emerging hallmark of disease is transcription of pathogen-associated molecular
patterns from within the genome–known as viral mimicry. We propose a statistical physics
framework to measure “selecti...
