Chemistry professor University of Göttingen (my views) #peptidomimetics | #proteomimetics | #incypro | co-founder #incircular | www.grossmannlab.com
Tom Grossmann
Loading...
We were excited to collaborate with Bruno Di Geronimo from @lynnkamerlin.bsky.social group on the stabilization of Salvia rosmarinus borneol dehydrogenase (BDH). In the preprint we explore two computational methods, put them into contrast and explore a subset of new variants. doi.org/10.64898/202...
Excited to see our report on an #INCYPRO stabilised D-stereospecific hydrolase featured on the the inside cover of the current Angewandte issue! doi.org/10.1002/anie...
Congrats to all coauthors and collaborators from the Bordusa Lab and Incircular.
#ProteinEngineering #Biocatalysis
We report an #INCYPRO stabilised D-stereospecific hydrolase which operates efficiently at 50°C in 10% ethanol!
The article in Angewandte Chemie originates from a collaboration with the Bordusa Lab and Incircular. Congrats to all authors!
#ProteinEngineering #Biocatalysis
doi.org/10.1002/anie...
Next up, Jannik Keyser Paulus from the group of @tomngrossmann.bsky.social in @uni-goettingen.de focussed on redox responsive peptide dimers to stabilise and release therapeutic dsRNA
1/3
#17GPS
After a decade @vuamsterdam.bsky.social I’m excited to share that I’m starting @uni-goettingen.de
I’m incredibly grateful for my supportive colleagues at the VU and looking now forward to the opportunities ahead. Big THANKS to everyone in the group who supported our research over the years!
Great to see our Highlight Review on TAV2b-derived RNA modulators online at Chemistry Letters doi.org/10.1093/chem...
Congrats to first author Marvin Albers! Read more about our RNA-targeting strategies also here:
-> doi.org/10.1002/anie...
-> doi.org/10.1093/nar/...
-> doi.org/10.1002/chem...
Stabilizing Proteins by Chemical Cross-Linking: Insights into Conformation, Unfolding, and Aggregation Using Native Ion Mobility Mass Spectrometry #AC pubs.acs.org/doi/10.1021/...
Greetings from the GRC on Artificial Molecular Switches and Motors! It’s exciting to see how the field has grown and is moving toward everyday applications—think photoswitchable tattoos!
Recent article from the lab published in @jacs.acspublications.org. Big congrats to first author Zainab Rashid for leading the study and great collaboration with @tomngrossmann.bsky.social and Jocelyne Vreede labs!😃
doi.org/10.1021/jacs...
#singlemolecule #dsRNA #RNAtherapeutics
Now that our new @jacs.acspublications.org paper is printed, let me show you what's so cool about the group B [FeFe]-hydrogenase from Thermosediminibacter oceani (ToHydA) 😎
doi.org/10.1021/jacs...
