Investigating viruses, using pipettes, #AI and coffee.
Learn more at the lab website: https://grovelab.github.io/
Check out our database of viral protein structure predictions: https://viro3d.cvr.gla.ac.uk/
Based at: @cvrinfo.bsky.social
Joe Grove
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The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes:
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
Video
Mart Krupovic
A new family of rolling-circle replication endonucleases widespread in archaeal viruses and plasmids. This family is unrelated to the HUH superfamily Reps, but distantly related to the bacterial Rep_trans enzymes.
@narjournal.bsky.social
academic.oup.com/nar/article/...
Mart Krupovic
Great delivery by Sarah Little from @grovearmada.bsky.social team @microbiologysociety.org : Scalable Screening of AI Designed Binders that Prevent Virus Entry
We are incredibly excited to see our most recent story out @nature.com today:HIV triggers CD4-signaling to remodel nuclear pores and license infection!A heroic effort led by our very own @d-mesner.bsky.social & @mattvxwhelan.bsky.social! @blizardinstitute.bsky.social Link: tinyurl.com/HIVNup 1/11
Our two-part analysis of the current MV Hondius Andes virus outbreak is now live, including reconstruction of the outbreak molecular clock dating of the closest known ancestors of the outbreak lineage.
Part 1: outbreak sequence reconstruction and rooting
virological.org/t/molecular-...
