Supramolecular Systems (th)at Work
www.unige.ch/sciences/chiorg/matile/
The Matile Group
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Traceable traceless delivery tags: The tasty title of our new paper in Helv. Chim. Acta refers to the dual function of asparagusic acid, thiol-mediated uptake and Golgi tracking, at best inner membrane leaflet, cis Golgi lumen and trafficking from threre.
onlinelibrary.wiley.com/doi/10.1002/...
Our new paper in ChemistryEurope applies electric-field catalysis under organic synthesis conditions to Jørgenson-Hayashi-type chemistry.
With amines separated from acids, EFC mechanisms with prolinol ethers differ from prolines:
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
In our new paper in Chem. Sci., a final firework culminates with flippers that are not only as big and as beautiful as it gets but also solve a real problem and provide access to the imaging of membrane tension in living cells over longer periods of time.
pubs.rsc.org/en/content/a...
This is a very special moment for us, a big old dream come true: Our new paper in JACS Au provides the conceptual mechanistic framework for electric-field catalysis (EFC) at high voltage under practical organic synthesis conditions.
Thank you JACS Au (GOA, ACS): pubs.rsc.org/en/content/a...
Congratulations to Dr. Nerea González-Sanchis for a successful PhD defense, the final flipper firework with beautiful structures that solve real problems. Very best wishes for the future!
A big thank you to the members of the jury, Sascha Hoogendoorn, Sander Wezenberg and Jerome Lacour.
This was the 2025 edition of the traditional group dinner in the Edelweiss, newly renovated, cheese fondue, meat fondue, chocolate fondue, live jodel, alphorn and kirsch
The current #1 Bestseller of Helv. Chim. Acta, the Journal of the Swiss Chemical Society, founded 1917, is our paper with the groups of Thomas Poulsen (Aarhus, Denmark) and Oliver Thorn-Seshold (Dresden, Germany): Thank you so much for reading!
onlinelibrary.wiley.com/journal/1522...
In our new review in Helv. Chim. Acta, we summarize the first decade of CPDs – cell-penetrating poly(disulfide)s - comprehensively. It was gratifying to see how useful their thiol-mediated uptake has become in practice, also in living animals.
onlinelibrary.wiley.com/doi/10.1002/...
Our new paper in Angew. Chem. could make thiol-mediated uptake more generally useful for the community, at last: Grafting CPDs to SOIs rather than the original grafting-from provides the fast bioconjugation needed.
Thank you, Angew. Chem. (open access): onlinelibrary.wiley.com/doi/10.1002/...
