Executive Editor of Cancer Discovery, published by AACR. Harvard BBS/Dana-Farber alum. Native New Yorker. Posts are my own. She/her https://aacrjournals.org/cancerdiscovery
Elizabeth McKenna
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Now online in Cancer Discovery @aacrjournals.bsky.social: Asynchronous Evolution of Epithelium and Stroma Differentiates Precursor Lesions from Pancreatic Cancer - by Ahmed Elhossiny, @fertiglab.bsky.social, Eileen Carpenter, Timothy Frankel, Marina Pasca di Magliano, et al. doi.org/10.1158/2159...
The June issue of Cancer Discovery @aacrjournals.bsky.social is online! The cover features work by Yan Zhang, Songhua Wang, Weiwei Ma,
Yuan Wang, et al. showing a role for tumor microtube expansion & neural synaptic pruning in GBM - Read that & more: aacrjournals.org/cancerdiscov...
Joan Massague giving the keynote at the EMBO Workshop on the Many Faces of Cancer Evolution - read his recent piece in Cancer Discovery @aacrjournals.bsky.social calling for an organ-informed precision oncology framework integrating site-imposed metastatic programs aacrjournals.org/cancerdiscov...
Dal tumore invisibile al tumore riconoscibile. Un nuovo studio IFOM su Cancer Discovery apre prospettive concrete per rendere visibili al sistema immunitario tumori che fino a ieri riuscivano a nascondersi.
📄 Paper → aacrjournals.org/cancerdiscov...
#IFOM #AIRC #Immunoterapia #Oncologia
I am very excited that our work on the evolution of clonal hematopoiesis throughout human life is now available (unedited version) online in Cancer Discovery @aacrjournals.bsky.social.
Huge congratulations to @nvmp.bsky.social and @francescoterenzi.bsky.social!
aacrjournals.org/cancerdiscov...
Now online in Cancer Discovery @aacrjournals.bsky.social: Senescent-like Neutrophils Shape Angiogenic Immunosuppressive Niches in CRC Liver Metastasis - by Zhihang Chen, Xiaoxue Ren, Yifan Zhang, Youmei Kang, Ye Yang, Xiaoxing Li, Jianting Long, Lixia Xu, Ming Kuang, et al. doi.org/10.1158/2159...
Now online in Cancer Discovery AACR Journals: A Spatial Atlas of Muscle-Invasive Bladder Cancer Reveals Lineage-Specific Vulnerabilities and Immune Architecture - by Kai Yu, Jianfeng Chen, Jianjun Gao, Linghua Wang, MD, PhD, et al. doi.org/10.1158/2159... @mdanderson.bsky.social
Now online in Cancer Discovery AACR Journals: Mismatch Repair-Proficient Colorectal Cancer Can Evade Immune Surveillance through an Intrinsic Suppressive Program - by Chiara Cattaneo, Sharon Scardellato, @bardellilab.bsky.social et al. doi.org/10.1158/2159... IFOM
Now online in Cancer Discovery @aacrjournals.bsky.social: The Evolution of Polyclonal Competition in Aging Hematopoiesis - by @nvmp.bsky.social, Francesco Terenzi, and @benjaminwerner.bsky.social doi.org/10.1158/2159... @qmbci.bsky.social
Couldn’t be happier to return to Rimini for the 3rd edition of the EMBO Workshop on the Many Faces of Cancer Evolution! Thanks @magnanilab.bsky.social @ciriellolab.bsky.social Céline Vallot, and Samra Turajlic for the invitation and congrats on another amazing meeting!
Abstract. Clonal hematopoiesis (CH) — the expansion of genetic variants in blood — is a prime example of somatic evolution. Although it often precedes malignant transformation, many aspects of this pr...