NephGen brings together scientists who use genetic evidence and innovative transdisciplinary approaches to prevent and treat kidney diseases.
SFB 1453 NephGen
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Congratulations to NephGen PIs Melanie Börries and Sven Diederichs and their groups on their practise changing publication in @natgenet.nature.com 👏👏
#MedSky #OncoSky
rdcu.be/eUbf3
www.science.org/doi/10.1126/...
Pascal Schlosser and Matthias Wuttke, our
@sfb1453.bsky.social representation and speakers at this year's #kidneywk
SFB 1453 NephGen
NephGen speaker Anna Köttgen attendend the first ERA Science Meeting in November to further improve precision medicine in genetic kidney diseases #NephSky #MedSky
See link for more details 👇
www.linkedin.com/posts/europe...
Proteinuria causes ciliary elongation and actin cytoskeleton remodeling, revealing a key mechanism in kidney disease progression.
A new exciting and highly collaborative @sfb1453.bsky.social paper by NephGen groups Börries, Schell, and Kühn in @pnas.org
Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease | PNAS www.pnas.org/doi/10.1073/...
Together with four other Freiburg CRCs, @sfb1453.bsky.social joined the @friasunifreiburg.bsky.social workshop to discuss "What it takes to build and lead successful interdisciplinary research initiatives"
If you want to know more check out the great summary by our CRC 1597 colleagues t1p.de/wlkqd
Today we are celebrating #WorldKidneyDay20Years 🎉
#WorldKidneyDay
Christoph Schell, MD,PhD
Revealing lysine-specific histone demethylase 1a as a new target for kidney diseases
Tobias B. Huber & team show LSD1 regulates kidney development, and its dysfunction disrupts key kidney cells, leading to cyst formation in mouse and organoid models: doi.org/10.1172/jci....
SFB 1453 NephGen
Happy to share our paper in the frame of the @sfb1453.bsky.social project that got published in @jmolbiol.bsky.social
Tremendous work from @emymrikov.bsky.social and others, on how the scaffold protein PDZK1 interacts with the urate transporter URAT1.
⬇️
www.sciencedirect.com/science/arti...
Good start for 2026: Our work on mucociliary progenitors and how FOXI1 regulates them as well as ionocyte specification is now out and open access.
tinyurl.com/Bowden-Engel...
Congrats to all authors and thanks to @dfg.de @cibss.bsky.social @sfb1453.bsky.social @for5547.bsky.social for support!
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney
disease. Limited treatment options lead to renal failure in ...
Nature Genetics - Saturation mutagenesis screening examines 11,520 point mutations in the kinase domains of FGFR1, FGFR2, FGFR3 and FGFR4, identifying their activating and resistance properties to...
✨ On November 27–28, the first ERA Science Meeting took place in Barcelona, Spain
🧬 This exclusive, invitation-only event brought together leading experts to shape a roadmap for implementing precisi...
The transcription factor Foxi1 regulates ionocytes across species and organs and it is associated with several human diseases, but its function in epidermis remains unclear. This study shows that low ...
The renal solute carrier URAT1 (SLC22A12) is essential for urate homeostasis, with loss-of-function linked to renal hypouricemia, nephrolithiasis and …
