Focus on developing proteomics technologies.
https://www.chem.ox.ac.uk/people/shabaz-mohammed
https://www.bioch.ox.ac.uk/research/mohammed
https://scholar.google.co.uk/citations?hl=en&user=6FdXeiwAAAAJ&view_op=list_works&sortby=pubdate
Shabaz Lab
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Short write-up of our journey. Searching for T cell transcription factors, Marc v/d Wetering stumbled across Wnt signaling. Vladja Korinek linked Wnt to colon cancer and crypt biology. Nick Barker discovered the gut stem cell. Toshi Sato invented organoids authors.elsevier.com/a/1n3No6tu0C...
There's a good Simpsons gag in here.
www.tomshardware.com/tech-industr...
Video
Hans Clevers
Shabaz Lab
Meet Chris Crittenden, our most recent #FacesOfMassSpec feature. At @Genentech, Chris uses tandem mass spectrometry to support clinical candidates while also championing mentorship and scientific collaboration. https://bit.ly/3RaRCRu
(MS Reviews) Carlito B. Lebrilla: Building Instruments, Fields and Opportunities From the Ground up: Mass Spectrometry Reviews, EarlyView. #MassSpectromRev #MassSpecRSS
Meet Chris Crittenden, our most recent #FacesOfMassSpec feature. At @Genentech, Chris uses tandem mass spectrometry to support clinical candidates while also championing mentorship and scientific collaboration. https://bit.ly/3RaRCRu
(ACS Anal Chem) [ASAP] Large-Scale Stereolithography Precision Manufactured Solid Cone-Jet Emitters for Electrospray Mass Spectrometry: Analytical ChemistryDOI: 10.1021/acs.analchem.6c02479 #MassSpecRSS #ACSAChem
Between 1985--2023, MIT's faculty grew 9%. Administrative staff grew 189%. 📈 Why? In new @pnas.org paper, we use dynamical system model to show administrative bloat can emerge without empire-building--just from well-intentioned problem-solving gone awry
www.pnas.org/doi/10.1073/...
We've just published a preprint describing GlyComboCLI, a command-line tool for glycan composition assignment in MS data. Open-source, FAIR-compliant, and built for integration into automated bioinformatic workflows. #glycotime
Link: www.biorxiv.org/content/10.6...
Well, its out. Honored to play a small part in this huge project using multi-omics to profile human biology and variations at unprecedented scale.
www.sciencedirect.com/science/arti...
Thanks to a great team of co-authors and collaborators!
@fbmh-uom.bsky.social @uom-dcs.bsky.social
ASMS
Kermit Murray
Kermit Murray
🔬 New preprint from KPL ApS: Arg-C Zero, recombinant arginyl endopeptidase with >99% cleavage efficiency, R-P bond cleavage, acid-compatible labile PTM workflows, and histone analysis without derivatization.
📄 doi.org/10.64898/202...
🛒 kplbio.com/arg-c-zero/
#Proteomics #MassSpec #PTM #Enzymes
Despite extensive research, molecular differences in human populations and the influence of ancestry, age, geography, and diet are poorly understood. …
