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Molecular Microscopy and Spectroscopy Lab (https://vicidominilab.github.io) at the @iitalk.bsky.social. "A #SPADarray detector in any laser-scanning microscope"
VicidominiLab









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Today @laurent-le.bsky.social introduced our lab activities at @gdrimabio.bsky.social. #SPADarray detectors are changing optical microscopy. We use them for #photonresolvedmicroscopy, extracting more information from every detected photon. 📢 PhD position open. @iitalk.bsky.social
🎉 Aujourd'hui c'était le lancement des rencontres 2026 du GDR Imabio. 🔬La 1ère session, "imaging deeper, imaging faster: pushing spatio-temporal limits", a mis en lumière les développements récents permettant d’explorer les systèmes biologiques avec une résolution et une vitesse toujours accrues.
BrightEyes-FFS: an open-source platform for comprehensive analysis of fluorescence fluctuation spectroscopy experiments with small detector arrays doi.org/10.1088/2515... via @ioppublishing.bsky.social
Last preprint from @vicidominilab.bsky.social with @murat-sunbul.bsky.social! First live-cell diffusivity analysis of lncRNA NEAT1-1, using 🧬biRhoBAST and 🔬FFS. Beyond paraspeckles and microspeckles, we resolve distinct nanoscale complexes in the nucleoplasm. www.biorxiv.org/content/10.6...
Are the cells alright? 🧫🔬🤒@mariodelr.bsky.social is presenting #PhotoFiTT at #FOM2026, a tool to assess phototoxicity ☠️ in you fluorescence microscopy assay developed @HenriquesLab. doi.org/10.1038/s414...
It was fun writing this with David @dgershlick.bsky.social! Check it our if you want to hear our view on small #GTPases networks in endosomal trafficking :) part of the themed issue on Membrane trafficking edited by @fromme-lab.bsky.social and Philippe Chavrier www.sciencedirect.com/science/arti...
Brightness demixing: a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on brightness. @slfort.bsky.social @laurent-le.bsky.social @ismolab.bsky.social @instlangevin.bsky.social www.nature.com/articles/s41...
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Delighted to share our preprint describing COMET, a new approach to drift correction for #SMLM, which performs exceptionally well in practice. Check out the benchmarking results compared to other methods! :) Thanks to @lreinkensmeier.bsky.social for a superb effort. www.biorxiv.org/cgi/content/...
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For EMBO Young Investigator Erdinc Sezgin, being part of the EMBO Young Investigator Programme is a chance to connect with top scientists and build an international “#research ecosystem” to advance #biophysics in medicine. 🧪 https://www.embo.org/people/bridging-disciplines/ #LifeSciences #networking
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How many photons do you need to measure a fluorescence lifetime? We are proud to release HILIGTHer, a #FLIM #DigitalTwin designed to simulate most features of time-domain FLIM systems, just announced at #FOM2026 and incredibly well-received. Beta release now available: github.com/HiLIGHT-HORI...
BrightEyes-FFS: an open-source platform for comprehensive analysis of fluorescence fluctuation spectroscopy experiments with small detector arrays, Slenders, Eli, Perego, Eleonora, Zappone, Sabrina, V...
BrightEyes-FFS: an open-source platform for comprehensive analysis of fluorescence fluctuation spectroscopy experiments with small detector arrays
doi.org
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Endosomal GTPases, while often used as markers for specific endosomal organelles, functionalize the surface of endosomal compartments into biochemical…
www.sciencedirect.com
Dynamic GTPase networks reshaping endosomal organelle identities
2mo
Brightness demixing is a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on their brightness rather than their spectral properties. As this ...
www.nature.com
Brightness demixing for simultaneous multi-target imaging in 3D single-molecule localization microscopy - Nature Methods
VicidominiLab
VicidominiLab
GdR ImaBio
Sabrina Zappone
Hannah Heil
Nature Methods
Fran Bottanelli
EMBO
Mark Bates
Alessandro Esposito 👨‍🔬🔬🧬👨‍👩‍👧🇪🇺🏳️‍🌈