The rarely told story of DBS before DBS from an industry perspective. Thank you very much, Keith Mullett, for taking part in this interview! Tune in below:
A wave of new papers discuss the merits and limitations of lesion network mapping. #neuroskyence
By @avaskham.bsky.social
www.thetransmitter.org/brain-imagin...
Moreover, did you know that Stimulating Brains Episodes are now searchable – and citeable? Check the website for a transcript player with search functionality – great to check back to "something you've heard" on the show in some of the episodes. All transcripts also available on figshare etc.
How do you build a brain circuit treatment for patients with the most severe form of epilepsy? Start by finding the brain circuit target. Great talk by @rolstonjohn.bsky.social @braincircuits.bsky.social
When clinicians and researchers work together toward the goal of improving lives for those with #bipolardisorder, collaboration shifts how research progresses. Hear from Tracy Young-Pearse, PhD, on BD²'s integrated approach in the latest #InvestigatorInsights. 🧠
🧠 @foxmdphd.bsky.social and his BD² Discovery Research team at @mgbresearch.bsky.social are mapping brain circuits tied to specific bipolar symptoms—unlocking targeted neuromodulation treatments rather than one-size-fits-all approaches.
Where, exactly, does learning happen in the brain?
Out today in @nature.com, we identify a synaptic locus of birdsong learning and show that the circuit can be tuned to make birds learn faster - but at a cost. Read on👇 #neuroskyence 🧪 #prattle 💬 #bioacoustics
Shareable link: rdcu.be/fiyrS
Thank you @avaskham.bsky.social @thetransmitter.bsky.social for covering the ongoing discussion re lesion network mapping. It is commendable when a news publication covers both sides of an issue, and a great example of unbiased and responsible reporting.
Can lesion network mapping predict survival in children with brain tumors? Collaboration with UCL and @braincircuits.bsky.social in @nature.com suggests the answer is yes. Cutting the tumor off from this network may provide survival benefit.
www.nature.com/articles/s41...
Congratulations @shansiddiqi.bsky.social and Joe Taylor
@braincircuits.bsky.social on their paper In Mol Psych demonstrating the translational power of LNM and brain circuit therapeutics. It has already changed clinical TMS practice
@massgeneralbrigham.bsky.social @harvardmed.bsky.social.
Andreas Horn
The Transmitter
Michael Fox
Stimulating Brains
Combining a computational framework and optogenetic and chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapse...
Tumour network mapping of diffuse midline glioma (DMG) defines a conserved and prognostically important brain network in children with DMG, consistent with the hypothesis that DMGs exploit otherw...
What was deep brain stimulation before the Benabid era? Listen to this new episode with a very unique view behind the scenes at Medtronic developing DBS for pain, just in time for the Grenoble team to come in:
stimulatingbrains.org/78-keith-mul...
A wave of new papers discuss the merits and limitations of lesion network mapping. #neuroskyence
By @avaskham.bsky.social
www.thetransmitter.org/brain-imagin...
What was deep brain stimulation before the Benabid era? Listen to this new episode with a very unique view behind the scenes at Medtronic developing DBS for pain, just in time for the Grenoble team to come in:
stimulatingbrains.org/78-keith-mul...
Stimulating Brains
After a January paper questioned the validity of an approach called lesion network mapping, its users are pressure testing their results.
New paper in Molecular Psychiatry:
In patients with anxiety + depression, targeting a novel “anxiosomatic” circuit (dmPFC) outperforms standard dlPFC for anxiety—and is equally effective for depression.
Free link: rdcu.be/faL22
Full link: lnkd.in/e4WZTncu
But the bigger story is the pipeline
1/n
