Geospatial targeting of TB screening in Uganda reduced screening volume by 92%, increased TB yield by 10%, and cut costs by >90%. Surveillance data can help find more TB with fewer resources
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Late-onset CMV pneumonia can occur even 1 year after auto-HSCT, particularly in patients with profound CD4 lymphopenia. This case highlights the value of immune-guided surveillance and BALF mNGS in diagnosing complex infections in immunocompromised hosts.
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TB treatment is evolving—but persistence remains a major barrier. New evidence shows macrophage metabolism and redox state shape intracellular drug tolerance in Mtb. Host-directed strategies may enhance antibiotic efficacy and help shorten therapy ⏳
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