Her recent work uncovered a critical epigenetic mechanism driving brain metastasis in triple-negative breast cancer, identifying KDM6A as a key mediator and potential therapeutic target
š www.nature.com/articles/s41...
Seehawer et al. show that deletion of Kmt2c or Kmt2d promotes brain metastasis in mouse models of triple-negative breast cancer due to altered KDM6A activity and upregulated MMP3 expression, which may...